'Giving #boosters #COVID shots in the same arm as the first dose was given, elicits higher levels of neutralizing antibodies and spike-specific CD8 T cells.
This is thought to be due to stimulation of the same lymph nodes that were used for priming (the initial vaccination)"
Summary by Dr Ruth Crystal
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00308-0/fulltext